Dr. Mohamad Abdouh
The Leonard Ellen Ocular Pathology Fellowship
One goal of our laboratory is to understand the mechanisms governing ocular melanoma progression and to try to find novel therapies. Indeed, the prognosis is very poor for patients, as the mortality rates have not improved, owing to low efficacy of newly-proposed therapeutic strategies. Nowadays, radiotherapy is still the frontline intervention for most patients with ocular melanoma, but this treatment compromises visual acuity because of several intraocular complications. This illustrates a need for combined therapies aimed at reducing radiation doses. My goal, along with the team of Dr. Miguel Burnier, is to search for valuable molecular targets and develop an effective combined therapy to control intraocular disease, mitigate radiation-induced complications, and inhibit disease metastasis.